Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Immunology

Vitamins prime immunity

The finding that derivatives of vitamin B can bind to an antigen-presenting protein that stimulates specialized immune cells suggests a novel mechanism by which the immune system detects microbial infections. See Article p.717

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Modes of antigen presentation.

References

  1. Chun, R. F., Adams, J. S. & Hewison, M. Expert Rev. Clin. Pharmacol. 4, 583–591 (2011).

    Article  CAS  Google Scholar 

  2. Hall, J. A., Grainger, J. R., Spencer, S. P. & Belkaid, Y. Immunity 35, 13–22 (2011).

    Article  CAS  Google Scholar 

  3. Kjer-Nielsen, L. et al. Nature 491, 717–723 (2012).

    Article  ADS  CAS  Google Scholar 

  4. Treiner, E. et al. Nature 422, 164–169 (2003).

    Article  ADS  CAS  Google Scholar 

  5. Huang, S. et al. Proc. Natl Acad. Sci. USA 106, 8290–8295 (2009).

    Article  ADS  CAS  Google Scholar 

  6. Gold, M. C. et al. PLoS Biol. 8, e1000407 (2010).

    Article  Google Scholar 

  7. Le Bourhis, L. et al. Nature Immunol. 11, 701–708 (2010).

    Article  CAS  Google Scholar 

  8. Chua, W.-J. et al. Infect. Immun. 80, 3256–3267 (2012).

    Article  CAS  Google Scholar 

  9. Chiba, A. Arthritis Rheum. 64, 153–161 (2012).

    Article  CAS  Google Scholar 

  10. Nicholson, J. K. et al. Science 336, 1262–1267 (2012).

    Article  ADS  CAS  Google Scholar 

  11. Said, H. M. Biochem. J. 437, 357–372 (2011).

    Article  CAS  Google Scholar 

  12. Kunisawa, J., Hashimoto, E., Ishikawa, I. & Kiyono, H. PLoS ONE 7, e32094 (2012).

    Article  ADS  CAS  Google Scholar 

  13. Koenig, J. E. et al. Proc. Natl Acad. Sci. USA 108 (suppl. 1), 4578–4585 (2011).

    Article  ADS  MathSciNet  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Wei-Jen Chua or Ted H. Hansen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chua, WJ., Hansen, T. Vitamins prime immunity. Nature 491, 680–681 (2012). https://doi.org/10.1038/491680a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/491680a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing