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Reproductive biology

Stem cells bear eggs

Researchers have coaxed cultured embryonic stem cells to develop into eggs that then give rise to normal offspring. The discovery should help to decode the molecular basis of gamete formation and might lead to treatments for infertility.

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Figure 1: Oogenesis from cultured stem cells.

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Correspondence to Konrad Hochedlinger.

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Cheloufi, S., Hochedlinger, K. Stem cells bear eggs. Nature 491, 535–536 (2012). https://doi.org/10.1038/491535a

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