Developing therapeutic drugs that target peptide receptors is challenging. The structure of one of these G-protein-coupled receptors, NTS1, activated and bound to a peptide, provides an excellent starting point. See Article p.508
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Notes
*This article and the paper under discussion2 were published online on 10 October 2012.
References
Griebel, G. & Holsboer, F. Nature Rev. Drug Discov. 11, 462–478 (2012).
White, J. F. et al. Nature 490 (2012).
Granier, S. et al. Nature 485, 400–404 (2012).
Manglik, A. et al. Nature 485, 321–326 (2012).
Thompson, A. A. et al. Nature 485, 395–399 (2012).
Wu, H. et al. Nature 485, 327–332 (2012).
Hausch, F. Angew. Chem. Int. Edn Engl. 47, 3314–3316 (2008).
Rasmussen, S. G. F. et al. Nature 469, 175–180 (2011).
Rosenbaum, D. M. et al. Science 318, 1266–1273 (2007).
Warne, T. et al. Nature 469, 241–244 (2011).
Warne, T. et al. Nature 454, 486–491 (2008).
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Hausch, F., Holsboer, F. Snapshot of an activated peptide receptor. Nature 490, 492–493 (2012). https://doi.org/10.1038/nature11634
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DOI: https://doi.org/10.1038/nature11634
