Dietary lack of a single amino acid impairs intestinal immunity in mice, altering the guts microbial community and leaving it vulnerable to damage. The finding helps to explain how malnutrition favours gut inflammation. See Letter p.477
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Scrimshaw, N. S., Taylor, C. E. & Gordon, J. E. Monogr. Ser. World Health Organ. 57, 3–329 (1968).
Hashimoto, T. et al. Nature 487, 477–481 (2012).
Kleta, R. et al. Nature Genet. 36, 999–1002 (2004).
Salzman, N. H. et al. Nature Immunol. 11, 76–82 (2010).
Peter, C., Waldmann, H. & Cobbold, S. P. Curr. Opin. Immunol. 22, 655–661 (2010).
Opitz, C. A. et al. Nature 478, 197–203 (2011).
Munn, D. H. et al. Science 281, 1191–1193 (1998).
Veldhoen, M. et al. Nature 453, 106–109 (2008).
Li, Y. et al. Cell 147, 629–640 (2011).
Kiss, E. A. et al. Science 334, 1561–1565 (2011).
Ghia, J. E. et al. Gastroenterology 137, 1649–1660 (2009).
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Izcue, A., Powrie, F. Malnutrition promotes rogue bacteria. Nature 487, 437–439 (2012). https://doi.org/10.1038/487437a
Published:
Issue Date:
DOI: https://doi.org/10.1038/487437a
