Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Virology

Bird flu in mammals

An engineered influenza virus based on a haemagglutinin protein from H5N1 avian influenza, with just four mutations, can be transmitted between ferrets, emphasizing the potential for a human pandemic to emerge from birds. See Letter p.420

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Avian haemagglutinins transmissible in mammals.

References

  1. Imai, M. et al. Nature http://dx.doi.org/10.1038/nature10831 (2012).

  2. Jackson, S. et al. J. Virol. 83, 8131–8140 (2009).

    Article  CAS  Google Scholar 

  3. Maines, T. R. et al. Proc. Natl Acad. Sci. USA 103, 12121–12126 (2006).

    Article  ADS  CAS  Google Scholar 

  4. Maines, T. R. et al. Virology 413, 139–147 (2011).

    Google Scholar 

  5. Chen, L.-M. et al. Virology 422, 105–113 (2012).

    Article  CAS  Google Scholar 

  6. Stevens, J. et al. J. Mol. Biol. 381, 1382–1934 (2008).

    Article  CAS  Google Scholar 

  7. Sorrell, E. M., Wan, H., Araya, Y., Song, H. & Perez, D. R. Proc. Natl Acad. Sci. USA 106, 7565–7570 (2009).

    Article  ADS  CAS  Google Scholar 

  8. Belser, J. A., Maines, T. R., Tumpey, T. M. & Katz, J. M. Expert Rev. Mol. Med. 12, e39 (2010).

    Article  Google Scholar 

  9. Sorrell, E. et al. Curr. Opin. Virol. 1, 635–642 (2011).

    Article  CAS  Google Scholar 

  10. Cline, T. D. et al. J. Virol. 85, 12262–12270 (2011).

    Article  CAS  Google Scholar 

  11. Octaviani, C. P., Ozawa, M., Yamada, S., Goto, H. & Kawaoka, Y. J. Virol. 84, 10918–10922 (2010).

    Article  CAS  Google Scholar 

  12. Nidom, C. A. et al. Emerg. Infect. Dis. 16, 1515–1523 (2010).

    Article  Google Scholar 

  13. Yamada, S. et al. Nature 444, 378–382 (2006).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Hui-Ling Yen or Joseph Sriyal Malik Peiris.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yen, HL., Peiris, J. Bird flu in mammals. Nature 486, 332–333 (2012). https://doi.org/10.1038/nature11192

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature11192

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing