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Stem cells

The clock within

The molecular clock machinery regulates organisms' responses to daily variations in the environment. One unexpected response seems to be temporal fine-tuning of stem-cell behaviour in the skin. See Article p.209

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Figure 1: Stem cells and circadian oscillations.

References

  1. Schibler, U. & Sassone-Corsi, P. Cell 111, 919–922 (2002).

    Article  CAS  Google Scholar 

  2. Janich, P. et al. Nature 480, 209–214 (2011).

    Article  ADS  CAS  Google Scholar 

  3. Zhang, E. E. & Kay, S. A. Nature Rev. Mol. Cell Biol. 11, 764–776 (2010).

    Article  CAS  Google Scholar 

  4. Méndez-Ferrer, S., Lucas, D., Battista, M. & Frenette, P. S. Nature 452, 442–447 (2008).

    Article  ADS  Google Scholar 

  5. Fu, L., Patel, M. S., Bradley, A., Wagner, E. F. & Karsenty, G. Cell 122, 803–815 (2005).

    Article  CAS  Google Scholar 

  6. Shimba, S. et al. Proc. Natl Acad. Sci. USA 102, 12071–12076 (2005).

    Article  ADS  CAS  Google Scholar 

  7. Grimaldi, B. et al. Cell Metab. 12, 509–520 (2010).

    Article  CAS  Google Scholar 

  8. Yagita, K. et al. Proc. Natl Acad. Sci. USA 107, 3846–3851 (2010).

    Article  ADS  CAS  Google Scholar 

  9. Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M. & Sassone-Corsi, P. Science 324, 654–657 (2009).

    Article  ADS  CAS  Google Scholar 

  10. Ramsey, K. M. et al. Science 324, 651–654 (2009).

    Article  ADS  CAS  Google Scholar 

  11. Nakada, D., Levi, B. P. & Morrison, S. J. Neuron 70, 703–718 (2011).

    Article  CAS  Google Scholar 

  12. Masri, S. & Sassone-Corsi, P. Nature Neurosci. 13, 1324–1329 (2010).

    Article  CAS  Google Scholar 

  13. Luis, N. M. et al. Cell Stem Cell 9, 233–246 (2011).

    Article  CAS  Google Scholar 

  14. Mejetta, S. et al. EMBO J. 30, 3635–3646 (2011).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Paolo Sassone-Corsi.

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Aguilar-Arnal, L., Sassone-Corsi, P. The clock within. Nature 480, 185–187 (2011). https://doi.org/10.1038/480185a

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