Maintaining an optimal cellular energy status requires sensing the levels of the adenine nucleotides ATP, ADP and AMP. Biochemical and structural studies of the enzyme AMPK provide insights into how this is achieved. See Letter p.230
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Hardie, D. How cells sense energy. Nature 472, 176–177 (2011). https://doi.org/10.1038/472176a
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DOI: https://doi.org/10.1038/472176a
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