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Structural biology

Proteins in dynamic equilibrium

Nature volume 468, pages 1046–1048 (2010)Cite this article

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Protein molecules in solution exist as an equilibrium of different conformations, but the sizes and shifts of these populations cannot be determined from static structures. A report now shows how they can be measured in solution.

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Figure 1: Conformational states of the Hck enzyme in solution.

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Authors and Affiliations

  1. Pau Bernadó is at the Institute for Research in Biomedicine, 08028-Barcelona, Spain. pau.bernado@irbbarcelona.org,

    Pau Bernadó

  2. Martin Blackledge is at the Institute de Biologie Structurale Jean-Pierre Ebel, Commissariat à l'Energie Atomique, CNRS, Université Joseph Fourier, Grenoble 38027, France. martin.blackledge@ibs.fr,

    Martin Blackledge

Authors
  1. Pau Bernadó
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  2. Martin Blackledge
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Bernadó, P., Blackledge, M. Proteins in dynamic equilibrium. Nature 468, 1046–1048 (2010). https://doi.org/10.1038/4681046a

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