One might think that aneuploidy — having an abnormal number of chromosomes — would be harmful, and would reduce an organism's fitness. Not necessarily: it all depends on the type of aneuploidy and the associated conditions. See Letter p.321
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References
Pavelka, N. et al. Nature 468, 321–325 (2010).
Duesberg, P., Li, R., Fabarius, A. & Hehlmann, R. Contrib. Microbiol. 13, 16–44 (2006).
Hede, K. J. Natl Cancer Inst. 97, 87–89 (2005).
Rancati, G. et al. Cell 135, 879–893 (2008).
Selmecki, A., Gerami-Nejad, M., Paulson, C., Forche, A. & Berman, J. Mol. Microbiol. 68, 624–641 (2008).
Torres, E. M. et al. Science 317, 916–924 (2007).
Torres, E. M. et al. Cell 143, 71–83 (2010).
Geiger, T., Cox, J. & Mann, M. PLoS Genet. 6, e1001090 (2010).
Springer, M., Weissman, J. S. & Kirschner, M. W. Mol. Syst. Biol. 6, 368 (2010).
Weaver, B. A. A. & Cleveland, D. W. Cancer Res. 67, 10103–10105 (2007).
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Berman, J. When abnormality is beneficial. Nature 468, 183–184 (2010). https://doi.org/10.1038/468183a
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DOI: https://doi.org/10.1038/468183a
