Aggregates and mutations of the proteins ataxin-2 and TDP-43 have been implicated in distinct neurodegenerative disorders. An interplay between these proteins is now reported for amyotrophic lateral sclerosis.
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Lagier-Tourenne, C., Cleveland, D. An expansion in ALS genetics. Nature 466, 1052–1053 (2010). https://doi.org/10.1038/4661052a
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DOI: https://doi.org/10.1038/4661052a
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