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  • Volume 466
  • Issue 7303
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  • Figure 3

Figure 3: Population structure inferred by ADMIXTURE analysis.

From The genome-wide structure of the Jewish people

  • Doron M. Behar1, 2, 14,
  • Bayazit Yunusbayev2, 3, 14,
  • Mait Metspalu2, 14,
  • Ene Metspalu2,
  • Saharon Rosset4,
  • Jüri Parik2,
  • Siiri Rootsi2,
  • Gyaneshwer Chaubey2,
  • Ildus Kutuev2, 3,
  • Guennady Yudkovsky1, 5,
  • Elza K. Khusnutdinova3,
  • Oleg Balanovsky6,
  • Ornella Semino7,
  • Luisa Pereira8, 9,
  • David Comas10,
  • David Gurwitz11,
  • Batsheva Bonne-Tamir11,
  • Tudor Parfitt12,
  • Michael F. Hammer13,
  • Karl Skorecki1, 5,
  • Richard Villems2,
Journal name:
Nature
Volume:
466,
Pages:
238–242
Date published:
(08 July 2010)
DOI:
doi:10.1038/nature09103
Population structure inferred by ADMIXTURE analysis.

Each individual is represented by a vertical (100%) stacked column of genetic components proportions shown in colour for K = 8. The Jewish communities are labelled in colour and bold. T and B further specify Sephardi Jews from Turkey and Bulgaria, respectively. Populations introduced for the first time in this study and analysed together with the Human Genome Diversity Panel18 data are marked with an asterisk.

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Additional data

Primary authors

  1. These authors contributed equally to this work.

    • Doron M. Behar,
    • Bayazit Yunusbayev &
    • Mait Metspalu

Affiliations

  1. Molecular Medicine Laboratory, Rambam Health Care Campus, Haifa 31096, Israel

    • Doron M. Behar,
    • Guennady Yudkovsky &
    • Karl Skorecki
  2. Estonian Biocentre and Department of Evolutionary Biology, University of Tartu, Tartu 51010, Estonia

    • Doron M. Behar,
    • Bayazit Yunusbayev,
    • Mait Metspalu,
    • Ene Metspalu,
    • Jüri Parik,
    • Siiri Rootsi,
    • Gyaneshwer Chaubey,
    • Ildus Kutuev &
    • Richard Villems
  3. Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences, Ufa 450054, Russia

    • Bayazit Yunusbayev,
    • Ildus Kutuev &
    • Elza K. Khusnutdinova
  4. Department of Statistics and Operations Research, School of Mathematical Sciences, Tel Aviv University, Tel Aviv 69978, Israel

    • Saharon Rosset
  5. Rappaport Faculty of Medicine and Research Institute, Technion – Israel Institute of Technology, Haifa 31096, Israel

    • Guennady Yudkovsky &
    • Karl Skorecki
  6. Research Centre for Medical Genetics, Russian Academy of Medical Sciences, Moscow 115478, Russia

    • Oleg Balanovsky
  7. Dipartimento di Genetica e Microbiologia, Università di Pavia, Pavia 27100, Italy

    • Ornella Semino
  8. Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Porto 4200-465, Portugal

    • Luisa Pereira
  9. Faculdade de Medicina, Universidade do Porto, Porto 4200-319, Portugal

    • Luisa Pereira
  10. Institute of Evolutionary Biology (CSIC-UPF), CEXS-UPF-PRBB and CIBER de Epidemiología y Salud Pública, Barcelona 08003, Spain

    • David Comas
  11. Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel

    • David Gurwitz &
    • Batsheva Bonne-Tamir
  12. Department of the Languages and Cultures of the Near and Middle East, Faculty of Languages and Cultures, School of Oriental and African Studies (SOAS), University of London, London WC1H 0XG, UK

    • Tudor Parfitt
  13. ARL Division of Biotechnology, University of Arizona, Tucson, Arizona 85721, USA

    • Michael F. Hammer

Contributions

D.M.B. and R.V. conceived and designed the study. B.B.T., D.C., D.G., D.M.B., E.K.K., G.C., I.K., L.P., M.F.H., O.B., O.S., T.P. and R.V. provided DNA samples to this study. E.M., J.P. and G.Y. screened and prepared the samples for the autosomal genotyping. D.M.B., E.M., G.C., M.F.H. and Si.R. generated and summarized the database for the uniparental analysis. B.Y., M.M. and Sa.R. designed and applied the modelling methodology and statistical analysis. T.P. provided expert input regarding the relevant historical aspects. B.Y., D.M.B., K.S., M.F.H., M.M., R.V. and Sa.R. wrote the paper. B.Y., D.M.B. and M.M. contributed equally to the paper. All authors discussed the results and commented on the manuscript.

Competing financial interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to:

  • Doron M. Behar or
  • Karl Skorecki or
  • Richard Villems

The array data described in this paper are deposited in the Gene Expression Omnibus under accession number GSE21478.

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ISSN: 0028-0836
EISSN: 1476-4687
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