Toll receptors trigger immune responses through adaptor proteins and kinase enzymes. Structural studies reveal that hierarchical assembly of these proteins into a helical tower initiates downstream signalling events.
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Wasserman, S. Immunity takes a heavy Toll. Nature 465, 882–883 (2010). https://doi.org/10.1038/465882a
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DOI: https://doi.org/10.1038/465882a
