You might think that the partial symmetry of the molecule complanadine A makes it easy to prepare, but the reverse is true. Two syntheses of this compound offer insight into how to make partly symmetrical molecules.
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Snyder, S. Symmetrizing the unsymmetrical. Nature 465, 560–561 (2010). https://doi.org/10.1038/465560a
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DOI: https://doi.org/10.1038/465560a