In worms, neurons respond to low levels of environmental oxygen in a way that protects distant tissues from stress-induced cell death. The molecules that mediate this cell-cell signalling may be targets for cancer treatment.
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References
Sendoel, A., Kohler, I., Fellmann, C., Lowe, S. W. & Hengartner, M. O. Nature 465, 577–583 (2010).
Rankin, E. B. & Giaccia, A. J. Cell Death Differ. 15, 678–685 (2008).
Gartner, A., Boag, P. R. & Blackwell, T. K. WormBook doi:10.1895/wormbook.1.145.1 (2008).
Pak, B. J. et al. Oncogene 23, 30–38 (2004).
Michard, Q. et al. Free Radical Biol. Med. 44, 1023–1031 (2008).
Zhang, Y., Shao, Z., Zhai, Z., Shen, C. & Powell-Coffman, J. A. PLoS ONE 4, e6348 (2009).
Mehta, R. et al. Science 324, 1196–1198 (2009).
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Powell-Coffman, J., Coffman, C. Lack of oxygen aids cell survival. Nature 465, 554–555 (2010). https://doi.org/10.1038/465554a
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DOI: https://doi.org/10.1038/465554a
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Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling
Stem Cell Research & Therapy (2014)
