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Nature 461, 357-358 (17 September 2009) | doi:10.1038/461357a; Published online 16 September 2009

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Genomics: Hepatitis C virus gets personal

Shawn P. Iadonato1 & Michael G. Katze2

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Many people infected with the hepatitis C virus are not cured despite gruelling therapy. A human genetic variant that predicts successful treatment has been identified. So is personalized therapy now a possibility?

A staggering 170 million people are persistently infected with the hepatitis C virus (HCV), including 1–1.7% of people in the United States and roughly the same proportion in the European Union1.

  1. Shawn P. Iadonato is at Kineta, Inc., 307 Westlake Avenue North, Seattle, Washington 98109, USA.
    Email: siadonato@kinetabio.com
  2. Michael G. Katze is in the Department of Microbiology and the National Primate Center, University of Washington, Seattle, Washington 98195-8070, USA.
    Email: honey@u.washington.edu

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