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Nature 461, 181-182 (10 September 2009) | doi:10.1038/461181a; Published online 9 September 2009
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Project Director, Nouabalé-Ndoki Park Project
- Wildlife Conservation Society
- Congo Republic
Professor
- University of Cincinnati and Cincinnati Children's Research Foundation
- Cincinnati, OH
Cell biology: Sent by the scent of death
Christopher Gregory1
Abstract
Dying cells release 'find-me' factors that attract professional scavenger cells to engulf and digest them. These cellular invitations to dine can take unexpected forms.
About one million cells die every second in our bodies, often by the process of programmed cell death, or apoptosis. Dead cells are either expelled to the outside — for instance, by sloughing off of effete skin or gut cells — or are rapidly engulfed by healthy neighbours or professional scavenger cells.
- Christopher Gregory is at the Centre for Inflammation Research, University of Edinburgh and ImmunoSolv Limited, Edinburgh EH16 4SB, UK.
Email: chris.gregory@ed.ac.uk
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RESEARCH
Hyperglycemia Enhances DNA Fragmentation After Transient Cerebral IschemiaJournal of Cerebral Blood Flow & Metabolism Original Article
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearanceNature Letters to Editor (10 Sep 2009)
