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From the following article:
Macrophage elastase kills bacteria within murine macrophages
A. McGarry Houghton, William O. Hartzell, Clinton S. Robbins, F. Xavier Gomis-Rüth & Steven D. Shapiro
Nature 460, 637-641(30 July 2009)
doi:10.1038/nature08181
Figure 1
MMP12 provides survival advantage in Gram-positive and Gram-negative infection.
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MMP12 improves bacterial clearance and survival in S. aureus pneumonia.
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MMP12 is required for early intracellular bacterial killing by macrophages.
Full size figure and legend (126K)Download Power Point slide (508K)Figure 4
MMP12 CTD possesses bactericidal activity.
Full size figure and legend (313K)Download Power Point slide (694K)Slides may be downloaded for educational use, according to the terms described in Nature Publishing Group's licensing policy.
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