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From the following article:

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

Yiguo Wang, Liliana Vera, Wolfgang H. Fischer & Marc Montminy

Nature 460, 534-537(23 July 2009)

doi:10.1038/nature08111

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Nuclear translocation and association of CRTC2 with ATF6alpha in response to ER stress.

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Figure 2

CRTC2 stimulates the expression of ER quality control genes through an association with ATF6alpha.

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Figure 3

CRTC2 mediates cross-talk between hepatic ER stress and fasting pathways.

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Figure 4

Reciprocal downregulation of ATF6alpha and upregulation of CREB in obesity.

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