
TY  - JOUR
AU  - Mair, W.
AU  - Dillin, A.
TI  - Aging and survival: the genetics of life span extension by dietary restriction
JA  - Annu. Rev. Biochem.
PY  - 2008///
VL  - 77
SP  - 727
EP  - 754
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1146/annurev.biochem.77.061206.171059
N1  - 10.1146/annurev.biochem.77.061206.171059
UR  - http://dx.doi.org/10.1146/annurev.biochem.77.061206.171059
ER  -

TY  - JOUR
AU  - Pirozzi, G.
TI  - Identification of novel human WW domain-containing proteins by cloning of ligand targets
JA  - J. Biol. Chem.
PY  - 1997///
VL  - 272
SP  - 14611
EP  - 14616
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1074/jbc.272.23.14611
N1  - 10.1074/jbc.272.23.14611
UR  - http://dx.doi.org/10.1074/jbc.272.23.14611
ER  -

TY  - JOUR
AU  - Huang, K.
TI  - A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis
JA  - Gene
PY  - 2000///
VL  - 252
SP  - 137
EP  - 145
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/S0378-1119(00)00216-X
N1  - 10.1016/S0378-1119(00)00216-X
UR  - http://dx.doi.org/10.1016/S0378-1119(00)00216-X
ER  -

TY  - JOUR
AU  - Astin, J. W.
AU  - O/'Neil, N. J.
AU  - Kuwabara, P. E.
TI  - Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1
JA  - DNA Repair (Amst.)
PY  - 2008///
VL  - 7
SP  - 267
EP  - 280
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.dnarep.2007.10.004
N1  - 10.1016/j.dnarep.2007.10.004
UR  - http://dx.doi.org/10.1016/j.dnarep.2007.10.004
ER  -

TY  - JOUR
AU  - Lakowski, B.
AU  - Hekimi, S.
TI  - The genetics of caloric restriction in Caenorhabditis elegans
JA  - Proc. Natl Acad. Sci. USA
PY  - 1998///
VL  - 95
SP  - 13091
EP  - 13096
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1073/pnas.95.22.13091
N1  - 10.1073/pnas.95.22.13091
UR  - http://dx.doi.org/10.1073/pnas.95.22.13091
ER  -

TY  - JOUR
AU  - Mair, W.
AU  - Panowski, S. H.
AU  - Shaw, R. J.
AU  - Dillin, A.
TI  - Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans
JA  - PLoS One
PY  - 2009///
VL  - 4
SP  - e4535
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1371/journal.pone.0004535
N1  - 10.1371/journal.pone.0004535
UR  - http://dx.doi.org/10.1371/journal.pone.0004535
ER  -

TY  - JOUR
AU  - Bishop, N. A.
AU  - Guarente, L.
TI  - Two neurons mediate diet-restriction-induced longevity in C. elegans
JA  - Nature
PY  - 2007///
VL  - 447
SP  - 545
EP  - 549
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1038/nature05904
N1  - 10.1038/nature05904
UR  - http://dx.doi.org/10.1038/nature05904
ER  -

TY  - JOUR
AU  - Panowski, S. H.
AU  - Wolff, S.
AU  - Aguilaniu, H.
AU  - Durieux, J.
AU  - Dillin, A.
TI  - PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
JA  - Nature
PY  - 2007///
VL  - 447
SP  - 550
EP  - 555
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1038/nature05837
N1  - 10.1038/nature05837
UR  - http://dx.doi.org/10.1038/nature05837
ER  -

TY  - JOUR
AU  - Klass, M. R.
TI  - Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span
JA  - Mech. Ageing Dev.
PY  - 1977///
VL  - 6
SP  - 413
EP  - 429
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/0047-6374(77)90043-4
N1  - 10.1016/0047-6374(77)90043-4
UR  - http://dx.doi.org/10.1016/0047-6374(77)90043-4
ER  -

TY  - JOUR
AU  - Greer, E. L.
TI  - An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
JA  - Curr. Biol.
PY  - 2007///
VL  - 17
SP  - 1646
EP  - 1656
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.cub.2007.08.047
N1  - 10.1016/j.cub.2007.08.047
UR  - http://dx.doi.org/10.1016/j.cub.2007.08.047
ER  -

TY  - JOUR
AU  - Lin, K.
AU  - Hsin, H.
AU  - Libina, N.
AU  - Kenyon, C.
TI  - Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
JA  - Nature Genet.
PY  - 2001///
VL  - 28
SP  - 139
EP  - 145
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Ogg, S.
TI  - The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
JA  - Nature
PY  - 1997///
VL  - 389
SP  - 994
EP  - 999
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1038/40194
N1  - 10.1038/40194
UR  - http://dx.doi.org/10.1038/40194
ER  -

TY  - JOUR
AU  - Dillin, A.
TI  - Rates of behavior and aging specified by mitochondrial function during development
JA  - Science
PY  - 2002///
VL  - 298
SP  - 2398
EP  - 2401
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1126/science.1077780
N1  - 10.1126/science.1077780
UR  - http://dx.doi.org/10.1126/science.1077780
ER  -

TY  - JOUR
AU  - Feng, J.
AU  - Bussiere, F.
AU  - Hekimi, S.
TI  - Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
JA  - Dev. Cell
PY  - 2001///
VL  - 1
SP  - 633
EP  - 644
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/S1534-5807(01)00071-5
N1  - 10.1016/S1534-5807(01)00071-5
UR  - http://dx.doi.org/10.1016/S1534-5807(01)00071-5
ER  -

TY  - JOUR
AU  - Lee, S. S.
TI  - A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
JA  - Nature Genet.
PY  - 2003///
VL  - 33
SP  - 40
EP  - 48
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1038/ng1056
N1  - 10.1038/ng1056
UR  - http://dx.doi.org/10.1038/ng1056
ER  -

TY  - JOUR
AU  - Kimura, K. D.
AU  - Tissenbaum, H. A.
AU  - Liu, Y.
AU  - Ruvkun, G.
TI  - daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
JA  - Science
PY  - 1997///
VL  - 277
SP  - 942
EP  - 946
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1126/science.277.5328.942
N1  - 10.1126/science.277.5328.942
UR  - http://dx.doi.org/10.1126/science.277.5328.942
ER  -

TY  - JOUR
AU  - Bernassola, F.
AU  - Karin, M.
AU  - Ciechanover, A.
AU  - Melino, G.
TI  - The HECT family of E3 ubiquitin ligases: multiple players in cancer development
JA  - Cancer Cell
PY  - 2008///
VL  - 14
SP  - 10
EP  - 21
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.ccr.2008.06.001
N1  - 10.1016/j.ccr.2008.06.001
UR  - http://dx.doi.org/10.1016/j.ccr.2008.06.001
ER  -

TY  - JOUR
AU  - Hoppe, T.
TI  - Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing
JA  - Cell
PY  - 2000///
VL  - 102
SP  - 577
EP  - 586
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/S0092-8674(00)00080-5
N1  - 10.1016/S0092-8674(00)00080-5
UR  - http://dx.doi.org/10.1016/S0092-8674(00)00080-5
ER  -

TY  - JOUR
AU  - Qiu, X.
AU  - Fay, D. S.
TI  - ARI-1, an RBR family ubiquitin-ligase, functions with UBC-18 to regulate pharyngeal development in C. elegans
JA  - Dev. Biol.
PY  - 2006///
VL  - 291
SP  - 239
EP  - 252
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.ydbio.2005.11.045
N1  - 10.1016/j.ydbio.2005.11.045
UR  - http://dx.doi.org/10.1016/j.ydbio.2005.11.045
ER  -

TY  - JOUR
AU  - Fay, D. S.
TI  - The coordinate regulation of pharyngeal development in C. elegans by lin-35/Rb, pha-1, and ubc-18
JA  - Dev. Biol.
PY  - 2004///
VL  - 271
SP  - 11
EP  - 25
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.ydbio.2004.03.022
N1  - 10.1016/j.ydbio.2004.03.022
UR  - http://dx.doi.org/10.1016/j.ydbio.2004.03.022
ER  -

TY  - JOUR
AU  - Fay, D. S.
AU  - Large, E.
AU  - Han, M.
AU  - Darland, M.
TI  - lin-35/Rb and ubc-18, an E2 ubiquitin-conjugating enzyme, function redundantly to control pharyngeal morphogenesis in C. elegans
JA  - Development
PY  - 2003///
VL  - 130
SP  - 3319
EP  - 3330
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1242/dev.00561
N1  - 10.1242/dev.00561
UR  - http://dx.doi.org/10.1242/dev.00561
ER  -

TY  - JOUR
AU  - Wolkow, C. A.
AU  - Kimura, K. D.
AU  - Lee, M. S.
AU  - Ruvkun, G.
TI  - Regulation of C. elegans life-span by insulinlike signaling in the nervous system
JA  - Science
PY  - 2000///
VL  - 290
SP  - 147
EP  - 150
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1126/science.290.5489.147
N1  - 10.1126/science.290.5489.147
UR  - http://dx.doi.org/10.1126/science.290.5489.147
ER  -

TY  - JOUR
AU  - Apfeld, J.
AU  - Kenyon, C.
TI  - Regulation of lifespan by sensory perception in Caenorhabditis elegans
JA  - Nature
PY  - 1999///
VL  - 402
SP  - 804
EP  - 809
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1038/45544
N1  - 10.1038/45544
UR  - http://dx.doi.org/10.1038/45544
ER  -

TY  - JOUR
AU  - Parkes, T. L.
TI  - Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
JA  - Nature Genet.
PY  - 1998///
VL  - 19
SP  - 171
EP  - 174
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Alcedo, J.
AU  - Kenyon, C.
TI  - Regulation of C. elegans longevity by specific gustatory and olfactory neurons
JA  - Neuron
PY  - 2004///
VL  - 41
SP  - 45
EP  - 55
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/S0896-6273(03)00816-X
N1  - 10.1016/S0896-6273(03)00816-X
UR  - http://dx.doi.org/10.1016/S0896-6273(03)00816-X
ER  -

TY  - JOUR
AU  - Libina, N.
AU  - Berman, J. R.
AU  - Kenyon, C.
TI  - Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
JA  - Cell
PY  - 2003///
VL  - 115
SP  - 489
EP  - 502
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/S0092-8674(03)00889-4
N1  - 10.1016/S0092-8674(03)00889-4
UR  - http://dx.doi.org/10.1016/S0092-8674(03)00889-4
ER  -

TY  - JOUR
AU  - Sheaffer, K. L.
AU  - Updike, D. L.
AU  - Mango, S. E.
TI  - The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging
JA  - Curr. Biol.
PY  - 2008///
VL  - 18
SP  - 1355
EP  - 1364
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.cub.2008.07.097
N1  - 10.1016/j.cub.2008.07.097
UR  - http://dx.doi.org/10.1016/j.cub.2008.07.097
ER  -

TY  - JOUR
AU  - Brenner, S.
TI  - The genetics of Caenorhabditis elegans
JA  - Genetics
PY  - 1974///
VL  - 77
SP  - 71
EP  - 94
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Dillin, A.
AU  - Crawford, D. K.
AU  - Kenyon, C.
TI  - Timing requirements for insulin/IGF-1 signaling in C. elegans
JA  - Science
PY  - 2002///
VL  - 298
SP  - 830
EP  - 834
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1126/science.1074240
N1  - 10.1126/science.1074240
UR  - http://dx.doi.org/10.1126/science.1074240
ER  -

TY  - GEN
AU  - Hope, I.
TI  - C. elegans: A Practical Approach
PY  - 1999///
SP  - 62
EP  - 63
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Mello, C. C.
AU  - Kramer, J. M.
AU  - Stinchcomb, D.
AU  - Ambros, V.
TI  - Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences
JA  - EMBO J.
PY  - 1991///
VL  - 10
SP  - 3959
EP  - 3970
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Leverson, J. D.
TI  - The APC11 RING-H2 finger mediates E2-dependent ubiquitination
JA  - Mol. Biol. Cell
PY  - 2000///
VL  - 11
SP  - 2315
EP  - 2325
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Xia, Y.
AU  - Pao, G. M.
AU  - Chen, H. W.
AU  - Verma, I. M.
AU  - Hunter, T.
TI  - Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein
JA  - J. Biol. Chem.
PY  - 2003///
VL  - 278
SP  - 5255
EP  - 5263
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1074/jbc.M204591200
N1  - 10.1074/jbc.M204591200
UR  - http://dx.doi.org/10.1074/jbc.M204591200
ER  -

TY  - JOUR
AU  - Carrano, A. C.
AU  - Eytan, E.
AU  - Hershko, A.
AU  - Pagano, M.
TI  - SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
JA  - Nature Cell Biol.
PY  - 1999///
VL  - 1
SP  - 193
EP  - 199
PB  - Macmillan Publishers Limited. All rights reserved
ER  -

TY  - JOUR
AU  - Kamath, R. S.
TI  - Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
JA  - Nature
PY  - 2003///
VL  - 421
SP  - 231
EP  - 237
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1038/nature01278
N1  - 10.1038/nature01278
UR  - http://dx.doi.org/10.1038/nature01278
ER  -

TY  - JOUR
AU  - Rual, J. F.
TI  - Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library
JA  - Genome Res.
PY  - 2004///
VL  - 14
SP  - 2162
EP  - 2168
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1101/gr.2505604
N1  - 10.1101/gr.2505604
UR  - http://dx.doi.org/10.1101/gr.2505604
ER  -

TY  - JOUR
AU  - Dillin, A.
AU  - Crawford, D. K.
AU  - Kenyon, C.
TI  - Timing requirements for insulin/IGF-1 signaling in C. elegans
JA  - Science
PY  - 2002///
VL  - 298
SP  - 830
EP  - 834
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1126/science.1074240
N1  - 10.1126/science.1074240
UR  - http://dx.doi.org/10.1126/science.1074240
ER  -

TY  - JOUR
AU  - Simmer, F.
TI  - Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions
JA  - PLoS Biol.
PY  - 2003///
VL  - 1
SP  - e12
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1371/journal.pbio.0000012
N1  - 10.1371/journal.pbio.0000012
UR  - http://dx.doi.org/10.1371/journal.pbio.0000012
ER  -

TY  - JOUR
AU  - Wolff, S.
TI  - SMK-1, an essential regulator of DAF-16-mediated longevity
JA  - Cell
PY  - 2006///
VL  - 124
SP  - 1039
EP  - 1053
PB  - Macmillan Publishers Limited. All rights reserved
M3  - 10.1016/j.cell.2005.12.042
N1  - 10.1016/j.cell.2005.12.042
UR  - http://dx.doi.org/10.1016/j.cell.2005.12.042
ER  -
