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From the following article:

A reevaluation of X-irradiation-induced phocomelia and proximodistal limb patterning

Jenna L. Galloway, Irene Delgado, Maria A. Ros & Clifford J. Tabin

Nature 460, 400-404(16 July 2009)

doi:10.1038/nature08117

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

X-irradiation of chick limbs causes phocomelia.

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Figure 2

Expression analysis of irradiated limbs reveals defects in differentiation but not specification of the proximal segments.

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Figure 3

Changes in cell death and proliferation do not explain the loss of proximal structures.

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Figure 4

X-irradiation disrupts chondrogenesis and does not convert proximal cells to distal fates.

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