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Nature 460, 123-127 (31 May 2009) | doi:10.1038/nature08087;

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Genome-wide silencing in Drosophila captures conserved apoptotic effectors

Apoptosis is a conserved form of programmed cell death firmly established in the aetiology, pathogenesis and treatment of many human diseases. Central to the core machinery of apoptosis are the caspases and their proximal regulators.

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