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Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

Lei Bu, Xin Jiang, Silvia Martin-Puig, Leslie Caron, Shenjun Zhu, Ying Shao, Drucilla J. Roberts, Paul L. Huang, Ibrahim J. Domian & Kenneth R. Chien

Nature 460, 113-117(2 July 2009)

doi:10.1038/nature08191

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Figure 1

Analysis of the in vivo expression of ISL1 in SHF-derived structures of the human fetal heart.

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Figure 2

ISL1 marks human ES-cell-derived cardiac progenitors.

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Figure 3

Isolation and characterization of human ES-cell-derived ISL1+ cardiac progenitors and their progeny.

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Figure 4

Expansion of human ES-cell-derived ISL1+ cardiac progenitors on Wnt3a feeders.

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