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Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

Ángel Raya, Ignasi Rodríguez-Pizà, Guillermo Guenechea, Rita Vassena, Susana Navarro, María José Barrero, Antonella Consiglio, Maria Castellà, Paula Río, Eduard Sleep, Federico González, Gustavo Tiscornia, Elena Garreta, Trond Aasen, Anna Veiga, Inder M. Verma, Jordi Surrallés, Juan Bueren & Juan Carlos Izpisúa Belmonte

Nature 460, 53-59(2 July 2009)

doi:10.1038/nature08129

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Figure 1

Derivation of patient-specific induced pluripotent stem cells from Fanconi anaemia patients.

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Figure 2

Molecular characterization of FA-iPS cell lines.

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Figure 3

Pluripotency of FA-iPS cells.

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Figure 4

Functional FA pathway in FA-iPS cells.

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Figure 5

Generation of disease-free haematopoietic progenitors from FA-iPS cell lines.

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