Access

News and Views

Nature 458, 585-586 (2 April 2009) | doi:10.1038/458585a; Published online 1 April 2009

Open Innovation Challenges

  • Methods to Analyze Consumer Emotions

    • Deadline: Jan 17 2010
    • Reward: $10,000 USD

    The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...

  • Single-cell Analysis Platform

    • Deadline: Dec 02 2009
    • Reward: $5,000 USD

    This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...

naturejobs

More science jobs
Post a job for free

Neuroscience: AMPA receptors get 'pickled'

Alexander C. Jackson1 & Roger A. Nicoll1

Top

In mediating fast synaptic communication in the brain, AMPA receptors require TARP auxiliary proteins. It seems that another distinct class of proteins also bind to AMPA receptors and regulate their function.

It is now well established that ion channels are not solitary creatures, but often have an entourage of auxiliary proteins. Indeed, voltage-gated potassium, sodium and calcium channels form stable complexes with an assortment of both cytoplasmic and transmembrane proteins that profoundly affect their localization and function1.

  1. Alexander C. Jackson and Roger A. Nicoll are in the Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California 94143, USA.
    Email: nicoll@cmp.ucsf.edu