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Editorials

Turkey censors evolution p259

Turkey's government has done more for science than many. A row over a censored magazine and a sacked editor could put the good work at risk.

doi:10.1038/458259a


Health highway p259

President Obama's funds for electronic health records should prompt research — and controversy.

doi:10.1038/458259b


Filling the void p260

As science journalism declines, scientists must rise up and reach out.

doi:10.1038/458260a


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Research Highlights

Planetary science: Fiery fountains p262

doi:10.1038/458262a


Evolution: Painful pairing p262

doi:10.1038/458262b


Chemistry: Buckyball expansion p262

doi:10.1038/458262c


Cancer therapeutics: Socking it to melanoma p262

doi:10.1038/458262d


Genomics: Staying in shape p262

doi:10.1038/458262e


Sexual selection: Cheap flights p262

doi:10.1038/458262f


Genomics: Big is beautiful p263

doi:10.1038/458263a


Molecular imaging: Nailing the molecule p263

doi:10.1038/458263b


Evolution: Fishy fangs p263

doi:10.1038/458263c


Materials: Five-star ice p263

doi:10.1038/458263d


Correction p263

doi:10.1038/458263e


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Journal Club

Journal club p263

Ahmad M. Khalil

doi:10.1038/458263f


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News

Europe's green billions p264

Clean-energy investments target eastern Europe, but it remains to be seen whether they will create as many new jobs as hoped.

Quirin Schiermeier

doi:10.1038/458264a


Society sues journal over right to reply p264

Row between Max Planck Society and Wiley escalates.

Alison Abbott

doi:10.1038/458264b


Scientists in bone battle p265

Native Americans lay claim to 10,000-year-old skeletons.

Rex Dalton

doi:10.1038/458265a


America's long hard road to climate-change law p266

What challenges lie ahead as the United States tries to construct a working system for greenhouse-gas regulation? Jeff Tollefson reports.

Jeff Tollefson

doi:10.1038/458266a


Big interest in heavy drugs p269

The drug industry is seeking profits by modifying hydrogen in existing medications.

Katharine Sanderson

doi:10.1038/458269a


Roche vows to keep Genentech culture p270

It will be business as usual despite merger, say bosses.

Erika Check Hayden

doi:10.1038/458270a


Incoming chief to tackle woes of US food and drug agency p271

Obama nominates Margaret 'Peggy' Hamburg as FDA chief.

Meredith Wadman

doi:10.1038/458271a


Yale climate-change institute launched p272

doi:10.1038/458272a


NIH research to become permanently open access p272

doi:10.1038/458272b


Maths mistake blamed for killing off 'clean coal' plant p272

doi:10.1038/458272c


Soundbites from Copenhagen p272

Views from the International Scientific Congress on Climate Change, 10–12 March.

doi:10.1038/458272d


Lighter Higgs boson harder to find p273

doi:10.1038/458273a


Hospital investigation reveals long-running fraud p273

doi:10.1038/458273b


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News Features

Science journalism: Supplanting the old media? p274

Science journalism is in decline; science blogging is growing fast. But can the one replace the other, asks Geoff Brumfiel.

doi:10.1038/458274a


Clinical epidemiology: Archived answers p278

The switch to electronic medical records opens up a potential wealth of data for researchers, if major obstacles can be overcome, reports Katharine Gammon.

doi:10.1038/458278a


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Correspondence

Diversity of funding sources and topics is key to survival p281

Brian Derby

doi:10.1038/458281a


Grant-writing offices would let scientists get on with research p281

Cecile Perrault

doi:10.1038/458281b


We need more insight into what's worth paying for p281

William Gunn

doi:10.1038/458281c


Backlogged system in Australia shuts out new investigators p281

Darren Saunders

doi:10.1038/458281d


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Essay

Do nations go to war over water? p282

Wendy Barnaby was asked to write a book about water wars — then the facts got in the way of her story.

Wendy Barnaby

doi:10.1038/458282a


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Books and Arts

When wise words are not enough p284

Thomas Homer-Dixon argues that opinion-makers must demonstrate a better grasp of how societies rise and fall if they are to steer nations successfully through many of this century's major crises.

Thomas Homer-Dixon

doi:10.1038/458284a


Universe in a box p285

Pedro Ferreira reviews Joseph Cornell and Astronomy: A Case for the Stars by Kirsten Hoving

doi:10.1038/458285a


A romp through science fiction p286

Stefano Tonzani reviews Nanovision: Engineering the Future by Colin Milburn

doi:10.1038/458286a


Disturbing the Arkansas river p287

Laura Spinney reviews Over The River, A Work in Progress

doi:10.1038/458287a


Not one to watch p287

Michael White reviews Watchmen

doi:10.1038/458287b


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News and Views

Spectroscopy: Handedness in quick time p289

The handedness of chiral molecules can be probed spectroscopically, but acquiring data can take hours, which is a problem for time-resolved studies. The latest method records such data in a flash.

Patrick H. Vaccaro

doi:10.1038/458289a

See also: Editor's summary


Cancer: The nuances of therapy p290

Oncologists use drugs that limit a tumour's blood supply to prevent its growth. Although the initial effects of these drugs are beneficial to patients, new data suggest that their long-term effects warrant further study.

Lee M. Ellis & David A. Reardon

doi:10.1038/458290a


50 & 100 years ago p291

doi:10.1038/458291a


Geophysics: Hot blanket in Earth's deep crust p292

Studies of rocks from Earth's crust suggest that the lower crust is a good thermal insulator. The knock-on effects of this finding are many — one being the crust's increased potential to generate more magma.

Jean Braun

doi:10.1038/458292a

See also: Editor's summary


Dinosaurs: Fuzzy origins for feathers p293

Cretaceous fossil deposits in China are famous for their feathered dinosaurs. But the surprising discovery of a herbivorous dinosaur with a filamentous coat raises fresh questions about the evolution of feathers.

Lawrence M. Witmer

doi:10.1038/458293a

See also: Editor's summary


Chemistry: Thinking outside the flask p294

Stephen Davey

doi:10.1038/458294a


Global change: West-side story of Antarctic ice p295

During the past five million years, the West Antarctic ice sheet has waxed and waned in size. A two-pronged reconstruction of that history provides clues to the ice sheet's future behaviour.

Philippe Huybrechts

doi:10.1038/458295a

See also: Editor's summary


Neuroscience: Secret of synapse specificity p296

How does the brain organize all of the information stored in memory? On the basis of a state-of-the-art imaging study of neuronal activity in real time, the answer seems to be, through specificity in space and time.

Scott M. Thompson & Hayley A. Mattison

doi:10.1038/458296a

See also: Editor's summary


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Brief Communications Arising

Hippopotamus and whale phylogeny pE1

Jonathan H. Geisler & Jessica M. Theodor

doi:10.1038/nature07776


Thewissen et al. reply pE5

J. G. M. Thewissen, Lisa Noelle Cooper, Mark T. Clementz, Sunil Bajpai & B. N. Tiwari

doi:10.1038/nature07775


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Articles

Activation of CaMKII in single dendritic spines during long-term potentiation p299

Seok-Jin R. Lee, Yasmin Escobedo-Lozoya, Erzsebet M. Szatmari & Ryohei Yasuda

doi:10.1038/nature07842

See also: Editor's summary | News and Views by Thompson & Mattison


Design and engineering of an O2 transport protein p305

Ronald L. Koder, J. L. Ross Anderson, Lee A. Solomon, Konda S. Reddy, Christopher C. Moser & P. Leslie Dutton

doi:10.1038/nature07841

See also: Editor's summary


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Letters

Femtosecond characterization of vibrational optical activity of chiral molecules p310

Hanju Rhee, Young-Gun June, Jang-Soo Lee, Kyung-Koo Lee, Jeong-Hyon Ha, Zee Hwan Kim, Seung-Joon Jeon & Minhaeng Cho

doi:10.1038/nature07846

See also: Editor's summary | News and Views by Vaccaro


Hybrid organic–inorganic rotaxanes and molecular shuttles p314

Chin-Fa Lee, David A. Leigh, Robin G. Pritchard, David Schultz, Simon J. Teat, Grigore A. Timco & Richard E. P. Winpenny

doi:10.1038/nature07847

See also: Editor's summary


Temperature-dependent thermal diffusivity of the Earth's crust and implications for magmatism p319

Alan G. Whittington, Anne M. Hofmeister & Peter I. Nabelek

doi:10.1038/nature07818

See also: Editor's summary | News and Views by Braun


Obliquity-paced Pliocene West Antarctic ice sheet oscillations p322

T. Naish, R. Powell, R. Levy, G. Wilson, R. Scherer, F. Talarico, L. Krissek, F. Niessen, M. Pompilio, T. Wilson, L. Carter, R. DeConto, P. Huybers, R. McKay, D. Pollard, J. Ross, D. Winter, P. Barrett, G. Browne, R. Cody, E. Cowan, J. Crampton, G. Dunbar, N. Dunbar, F. Florindo, C. Gebhardt, I. Graham, M. Hannah, D. Hansaraj, D. Harwood, D. Helling, S. Henrys, L. Hinnov, G. Kuhn, P. Kyle, A. Läufer, P. Maffioli, D. Magens, K. Mandernack, W. McIntosh, C. Millan, R. Morin, C. Ohneiser, T. Paulsen, D. Persico, I. Raine, J. Reed, C. Riesselman, L. Sagnotti, D. Schmitt, C. Sjunneskog, P. Strong, M. Taviani, S. Vogel, T. Wilch & T. Williams

doi:10.1038/nature07867

See also: Editor's summary | News and Views by Huybrechts


Modelling West Antarctic ice sheet growth and collapse through the past five million years p329

David Pollard & Robert M. DeConto

doi:10.1038/nature07809

See also: Editor's summary | News and Views by Huybrechts


An Early Cretaceous heterodontosaurid dinosaur with filamentous integumentary structures p333

Xiao-Ting Zheng, Hai-Lu You, Xing Xu & Zhi-Ming Dong

doi:10.1038/nature07856

See also: Editor's summary | News and Views by Witmer


Population genomics of domestic and wild yeasts p337

Gianni Liti, David M. Carter, Alan M. Moses, Jonas Warringer, Leopold Parts, Stephen A. James, Robert P. Davey, Ian N. Roberts, Austin Burt, Vassiliki Koufopanou, Isheng J. Tsai, Casey M. Bergman, Douda Bensasson, Michael J. T. O'Kelly, Alexander van Oudenaarden, David B. H. Barton, Elizabeth Bailes, Alex N. Nguyen, Matthew Jones, Michael A. Quail, Ian Goodhead, Sarah Sims, Frances Smith, Anders Blomberg, Richard Durbin & Edward J. Louis

doi:10.1038/nature07743

See also: Editor's summary


Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae p342

Joseph Schacherer, Joshua A. Shapiro, Douglas M. Ruderfer & Leonid Kruglyak

doi:10.1038/nature07670

See also: Editor's summary


Antiviral immunity in Drosophila requires systemic RNA interference spread p346

Maria-Carla Saleh, Michel Tassetto, Ronald P. van Rij, Bertsy Goic, Valérie Gausson, Bassam Berry, Caroline Jacquier, Christophe Antoniewski & Raul Andino

doi:10.1038/nature07712

See also: Editor's summary


Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses p351

Ye Zheng, Ashutosh Chaudhry, Arnold Kas, Paul deRoos, Jeong M. Kim, Tin-Tin Chu, Lynn Corcoran, Piper Treuting, Ulf Klein & Alexander Y. Rudensky

doi:10.1038/nature07674

See also: Editor's summary


Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells p357

Satohiro Okuda, Hiroki Tsutsui, Keiko Shiina, Stefanie Sprunck, Hidenori Takeuchi, Ryoko Yui, Ryushiro D. Kasahara, Yuki Hamamura, Akane Mizukami, Daichi Susaki, Nao Kawano, Takashi Sakakibara, Shoko Namiki, Kie Itoh, Kurataka Otsuka, Motomichi Matsuzaki, Hisayoshi Nozaki, Tsuneyoshi Kuroiwa, Akihiko Nakano, Masahiro M. Kanaoka, Thomas Dresselhaus, Narie Sasaki & Tetsuya Higashiyama

doi:10.1038/nature07882

See also: Editor's summary


The DNA-encoded nucleosome organization of a eukaryotic genome p362

Noam Kaplan, Irene K. Moore, Yvonne Fondufe-Mittendorf, Andrea J. Gossett, Desiree Tillo, Yair Field, Emily M. LeProust, Timothy R. Hughes, Jason D. Lieb, Jonathan Widom & Eran Segal

doi:10.1038/nature07667

See also: Editor's summary


Transmembrane passage of hydrophobic compounds through a protein channel wall p367

Elizabeth M. Hearn, Dimki R. Patel, Bryan W. Lepore, Mridhu Indic & Bert van den Berg

doi:10.1038/nature07678

See also: Editor's summary


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Naturejobs

Prospects

Stem cell recruits p371

Lifting the stem-cell ban has repercussions that go beyond science ethics and disease cures.

Gene Russo

doi:10.1038/nj7236-371a


Special Report

Personnel dilemma p372

The hiring of US science faculty members has slowed considerably. Karen Kaplan tracks the administrators who are trying to keep programmes intact.

Karen Kaplan

doi:10.1038/nj7236-372a


Career View

Louise Ryan, chief, mathematical and information sciences, Commonwealth Scientific and Industrial Research Organisation, Sydney, Australia p374

Biostatistician seeks to boost statistics research posts in Australia.

Virginia Gewin

doi:10.1038/nj7236-374a


A bill to care for carers p374

Congresswoman seeks legislation to provide grant extensions for federally funded scientists who need extended family leave.

Heidi Ledford

doi:10.1038/nj7236-374b


As simple as possible p374

Is my marketability more important than my curiosity?

Sam Walcott

doi:10.1038/nj7236-374c


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Futures

Takeaway p376

A word to the wise.

Tony Ballantyne

doi:10.1038/458376a


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