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Hypothesis

Nature 457, 977-980 (19 February 2009) | doi:10.1038/nature07749

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A hierarchical model for evolution of 23S ribosomal RNA

Konstantin Bokov1 & Sergey V. Steinberg1

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The emergence of the ribosome constituted a pivotal step in the evolution of life. This event happened nearly four billion years ago, and any traces of early stages of ribosome evolution are generally thought to have completely eroded away. Surprisingly, a detailed analysis of the structure of the modern ribosome reveals a concerted and modular scheme of its early evolution.

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The ion core in RNA folding

Nature Structural Biology News and Views (01 Jul 1997)