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Nature 457, 974-975 (19 February 2009) | doi:10.1038/457974b; Published online 18 February 2009
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Molecular biology: The long and short of RNAs
Piero Carninci1
Abstract
The known world of RNA is expanding faster than that of any other cellular building block. The latest additions are types of long and short non-coding RNAs formed by bidirectional transcription and unusual processing.
The relationship between DNA, RNA and protein is no longer as simple as we once thought — that specific genomic sequences are transcribed into messenger RNAs, which are then translated into proteins. In recent years, a flurry of studies has reported the existence of a large and growing family of non-protein-coding RNAs (ncRNAs), describing the different mechanisms of their transcription and their role in regulating gene expression.
- Piero Carninci is at the Omics Science Center, RIKEN Yokohama Institute, Yokohama, Kanagawa 230-0045, Japan.
Email: carninci@riken.jp
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