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Nature 456, 883-885 (18 December 2008) | doi:10.1038/456883a; Published online 17 December 2008

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Organometallic chemistry: Catalyst takes control to heart

Steven T. Diver1

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Some transition-metal catalysts control organic reactions so that, given a choice of two mirror-image products, only one forms. The metal atom in these catalysts has been ignored as a source of control — until now.

In a classic episode of The Simpsons, Homer encounters problems when he enters a three-dimensional world beyond the flat environs of his cartoon existence. Chemists can appreciate his culture shock because, although flat organic molecules are relatively easy to make, three-dimensional molecules are much more challenging — especially those containing chiral carbon atoms, which have four different groups attached.

  1. Steven T. Diver is in the Department of Chemistry, University at Buffalo, The State University of New York, 572 Natural Sciences Complex, Amherst, New York 14260-3000, USA.
    Email: diver@buffalo.edu

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