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From the following article:

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

Olga Martins de Brito & Luca Scorrano

Nature 456, 605-610(4 December 2008)

doi:10.1038/nature07534

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

MFN2 regulates morphology of the endoplasmic reticulum.

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Figure 2

MFN2 is required at the endoplasmic reticulum to juxtapose it to mitochondria.

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Figure 3

Juxtaposition between ER and mitochondria requires ER MFN2 and mitochondrial MFN2 or MFN1.

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Figure 4

ER MFN2 engages in homotypic or heterotypic interactions with mitochondrial MFNs.

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Figure 5

MFN2 regulates ER Ca2+ levels and its transfer to mitochondria.

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