Figures and Tables

From the following article:

Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin

Emma Byres, Adrienne W. Paton, James C. Paton, Jonas C. Löfling, David F. Smith, Matthew C. J. Wilce, Ursula M. Talbot, Damien C. Chong, Hai Yu, Shengshu Huang, Xi Chen, Nissi M. Varki, Ajit Varki, Jamie Rossjohn & Travis Beddoe

Nature 456, 648-652(4 December 2008)

doi:10.1038/nature07428

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Figure 1

Structural analysis of SubB-sialic acid interactions and comparison with other AB5 toxins.

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Figure 2

Fluorescence microscopy and Neu5Gc-dependent cytotoxicity.

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Figure 3

Neu5Gc-dependent binding of SubAB to human tissues and toxicity of SubAB in wild-type and Cmah-null mice.

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Table 1

Glycan array analysis of native SubAB and B subunit mutant SubABA12

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