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Nature 455, 1186-1187 (30 October 2008) | doi:10.1038/4551186a; Published online 29 October 2008

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Cell biology: A Listeria escape trick

Grace Y. Lam1 & John H. Brumell1

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Pathogens have many ways of subverting their hosts' molecular machinery. A striking example of such a ploy comes to light from investigations of the species of bacterium that causes listeriosis.

A recent outbreak of Listeria monocytogenes infection in Canada1 has to date claimed 20 lives out of 53 cases and is a stark reminder that these bacteria pose a serious threat to public health. Ingestion of contaminated food can have especially serious consequences for those at high risk — pregnant women, newborns, the elderly, and individuals with compromised immune systems.

  1. Grace Y. Lam and John H. Brumell are at the Institute of Medical Science, University of Toronto, and the Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada. John H. Brumell is also in the Department of Molecular Genetics, University of Toronto.
    Email: g.lam@utoronto.ca
    Email: john.brumell@sickkids.ca

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