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Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

Lyris M. F. de Godoy, Jesper V. Olsen, Jürgen Cox, Michael L. Nielsen, Nina C. Hubner, Florian Fröhlich, Tobias C. Walther & Matthias Mann

Nature 455, 1251-1254(30 October 2008)

doi:10.1038/nature07341

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Figure 1

Three strategies for in-depth quantification of the yeast proteome by SILAC labelling and high-resolution mass spectrometry.

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Figure 2

Proteome coverage.

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Figure 3

Quantitative differences between the haploid and diploid yeast proteome.

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Figure 4

Proteome and transcriptome changes of haploid versus diploid yeast.

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Table 1

Yeast ORFs identified by SILAC-based quantitative proteomics

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