Long-term exposure to cocaine changes the organization of synaptic connections within the addiction circuitry of the brain. This process might protect against the development and persistence of addiction.
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Judson Chandler, L., Kalivas, P. Brain's defence against cocaine. Nature 455, 743–744 (2008). https://doi.org/10.1038/455743a
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DOI: https://doi.org/10.1038/455743a
