Supplementary information

Supplementary Information

The file contains Supplementary Figures and Legends 1-4; Supplementary Tables 1-3.
Supplementary Figure 1 represents quantitation of Omomyc and c-Myc expression in mouse tissues; Supplementary Figure 2 shows no influence of long-term systemic Omomyc expression on mouse weight; Supplementary. Figure 3 demonstrates that systemic Omomyc expression suppresses hair re-growth; Supplementary Figure 4 shows that induction of Omomyc in TRE-Omomyc; -actin-rtTA mice recapitulates the intestinal and skin phenotypes of Doxycylin treated TREOmomyc;CMVrtTA mice and, additionally, elicits increased extramedullary hematopoiesis in spleen.
Supplementary Table 1 shows that long-term systemic Omomyc expression has no significant impact on blood chemistry; Supplementary Table 2 includes blood counts showing that Omomyc expression causes transient anemia; Supplementary Table 3 includes detailed list of number and genotype of mice used for the experiments.

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