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Nature 455, 606-607 (2 October 2008) | doi:10.1038/455606a; Published online 1 October 2008

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Applied physics: Virtues of diamond defects

Michael Romalis1

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A general method for detecting nuclear magnetic resonance signals from a single molecule has so far been elusive. Magnetic sensors that exploit crystal imperfections in diamond might make such a method a reality.

The phenomenon of nuclear magnetic resonance (NMR), which results from the interaction of the spin of an atomic nucleus with an external magnetic field, has successfully been exploited in such disparate techniques as the structural analysis of molecules (NMR spectroscopy) and structural and functional analysis of the human body (NMR imaging), thus spanning length-scales from ångstroms to metres. But these techniques have remained mostly bulk methods, in that they usually require more than a billion spins.

  1. Michael Romalis is in the Department of Physics, Princeton University, Princeton, New Jersey 08540, USA.
    Email: romalis@princeton.edu

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