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Nature ${rb.getVolume()}, 613-619 (2 October 2008) | doi:10.1038/nature07352;

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Open Innovation Challenges

Challenges in the development of an HIV-1 vaccine

The development of a safe and effective human immunodeficiency virus (HIV)-1 vaccine is a critically important global health priority. Despite recent advances in our understanding of HIV-1 pathogenesis and immunology, however, major scientific obstacles remain.

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