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Nature ${rb.getVolume()}, 674-678 (24 August 2008) | doi:10.1038/nature07317;
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Director, UQ Centre for Clinical Research
- University of Queensland, Brisbane, Australia
- Brisbane, Queensland, Australia
Director of Bioinformatics
- University of the Witwatersrand, Johannesburg
- Johannesburg, South Africa
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
The cellular innate immune system is essential for recognizing pathogen infection and for establishing effective host defence. But critical molecular determinants responsible for facilitating an appropriate immune response—following infection with DNA and RNA viruses, for example—remain to be identified.
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