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Structural biology

A moving story of receptors

Nature volume 455, pages 473–474 (2008)Cite this article

Animals sense light and chemical signals through proteins called G-protein-coupled receptors. The crystal structure of one such receptor in complex with a G-protein fragment shows how these receptors are activated.

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Figure 1: Activation of a G-protein-coupled receptor.

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Author information

Authors and Affiliations

  1. Thue W. Schwartz is at the Laboratory for Molecular Pharmacology, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark. tws@sund.ku.dk ,

    Thue W. Schwartz

  2. Wayne L. Hubbell is at the Jules Stein Eye Institute and the Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, USA. hubbellw@jsei.ucla.edu,

    Wayne L. Hubbell

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  1. Thue W. Schwartz
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Competing interests

Thue W. Schwartz is chief scientific officer at 7TM Pharma, a drug-discovery company that targets G-protein-coupled receptors

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Schwartz, T., Hubbell, W. A moving story of receptors. Nature 455, 473–474 (2008). https://doi.org/10.1038/455473a

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