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Nature 455, 304-308 (18 September 2008) | doi:10.1038/nature07367; Published online 17 September 2008
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Commentary The advent and development of organocatalysis
David W. C. MacMillan1
Abstract
The use of small organic molecules as catalysts has been known for more than a century. But only in the past decade has organocatalysis become a thriving area of general concepts and widely applicable asymmetric reactions. Here I present my opinion on why the field of organocatalysis has blossomed so dramatically over the past decade.
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