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From the following article:

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

Jelena Nedjic, Martin Aichinger, Jan Emmerich, Noboru Mizushima & Ludger Klein

Nature 455, 396-400(18 September 2008)

doi:10.1038/nature07208

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Constitutive autophagy in TECs.

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Figure 2

Epithelial differentiation in the absence of Atg5.

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Figure 3

Atg5 deficiency modulates selection of MHC-II-restricted TCR specificities and the abundance of a specific MHCp complex.

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Figure 4

Atg5 deficiency in thymic epithelium causes colitis and multiorgan lymphoid infiltration.

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