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Nature 454, 1115-1118 (23 July 2008) | doi:10.1038/nature07168;
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A blend of small molecules regulates both mating and development in Caenorhabditis elegans
In many organisms, population-density sensing and sexual attraction rely on small-molecule-based signalling systems. In the nematode Caenorhabditis elegans, population density is monitored through specific glycosides of the dideoxysugar ascarylose (the |[lsquo]|ascarosides|[rsquo]|) that promote entry into an alternative larval stage, the non-feeding and highly persistent dauer stage.
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