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Nature 454, 1059-1062 (28 August 2008) | doi:10.1038/4541059a; Published online 27 August 2008
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Systems biology: Reverse engineering the cell
Nicholas T. Ingolia1 & Jonathan S. Weissman1
Abstract
Borrowing ideas that were originally developed to study electronic circuits, two reports decipher how yeast reacts to changes in its environment by analysing the organism's responses to oscillating input signals.
Systems biology has certainly caught people's attention. But when pressed to define precisely what it is, let alone how it will complement classic reductionist approaches, concrete answers can be hard to find.
- Nicholas T. Ingolia and Jonathan S. Weissman are at the Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, and California Institute for Quantitative Biomedical Research, San Francisco, California 94158-2542, USA.
Email: weissman@cmp.ucsf.edu
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