TY - JOUR AU - Ahmed, R. AU - Byrne, J. A. AU - Oldstone, M. B. TI - Virus specificity of cytotoxic T lymphocytes generated during acute lymphocytic choriomeningitis virus infection: role of the H-2 region in determining cross-reactivity for different lymphocytic choriomeningitis virus strains JA - J. Virol. PY - 1984/// VL - 51 SP - 34 EP - 41 PB - Macmillan Publishers Limited. All rights reserved ER - TY - JOUR AU - Matloubian, M. AU - Concepcion, R. J. AU - Ahmed, R. TI - CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection JA - J. Virol. PY - 1994/// VL - 68 SP - 8056 EP - 8063 PB - Macmillan Publishers Limited. All rights reserved ER - TY - JOUR AU - Kunzendorf, U. AU - Ziegler, E. AU - Kabelitz, D. TI - FTY720-the first compound of a new promising class of immunosuppressive drugs JA - Nephrol. Dial. Transplant. PY - 2004/// VL - 19 SP - 1677 EP - 1681 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1093/ndt/gfh295 N1 - 10.1093/ndt/gfh295 UR - http://dx.doi.org/10.1093/ndt/gfh295 ER - TY - JOUR AU - Chisari, F. V. AU - Ferrari, C. TI - Hepatitis B virus immunopathology JA - Springer Semin. Immunopathol. PY - 1995/// VL - 17 SP - 261 EP - 281 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1007/BF00196169 N1 - 10.1007/BF00196169 UR - http://dx.doi.org/10.1007/BF00196169 ER - TY - JOUR AU - Day, C. L. TI - PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression JA - Nature PY - 2006/// VL - 443 SP - 350 EP - 354 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1038/nature05115 N1 - 10.1038/nature05115 UR - http://dx.doi.org/10.1038/nature05115 ER - TY - JOUR AU - Folgori, A. TI - Early impairment of hepatitis C virus specific T cell proliferation during acute infection leads to failure of viral clearance JA - Gut PY - 2006/// VL - 55 SP - 1012 EP - 1019 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1136/gut.2005.080077 N1 - 10.1136/gut.2005.080077 UR - http://dx.doi.org/10.1136/gut.2005.080077 ER - TY - JOUR AU - Wherry, E. J. AU - Blattman, J. N. AU - Murali-Krishna, K. AU - van der Most, R. AU - Ahmed, R. TI - Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment JA - J. Virol. PY - 2003/// VL - 77 SP - 4911 EP - 4927 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1128/JVI.77.8.4911-4927.2003 N1 - 10.1128/JVI.77.8.4911-4927.2003 UR - http://dx.doi.org/10.1128/JVI.77.8.4911-4927.2003 ER - TY - JOUR AU - Shiow, L. R. TI - CD69 acts downstream of interferon-[agr]/[bgr] to inhibit S1P1 and lymphocyte egress from lymphoid organs JA - Nature PY - 2006/// VL - 440 SP - 540 EP - 544 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1038/nature04606 N1 - 10.1038/nature04606 UR - http://dx.doi.org/10.1038/nature04606 ER - TY - JOUR AU - Mamalaki, C. TI - Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen JA - Dev. Immunol. PY - 1993/// VL - 3 SP - 159 EP - 174 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1155/1993/98015 N1 - 10.1155/1993/98015 UR - http://dx.doi.org/10.1155/1993/98015 ER - TY - JOUR AU - Brinkmann, V. TI - The immune modulator FTY720 targets sphingosine 1-phosphate receptors JA - J. Biol. Chem. PY - 2002/// VL - 277 SP - 21453 EP - 21457 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1074/jbc.C200176200 N1 - 10.1074/jbc.C200176200 UR - http://dx.doi.org/10.1074/jbc.C200176200 ER - TY - JOUR AU - Chiba, K. TI - FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors JA - Pharmacol. Ther. PY - 2005/// VL - 108 SP - 308 EP - 319 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1016/j.pharmthera.2005.05.002 N1 - 10.1016/j.pharmthera.2005.05.002 UR - http://dx.doi.org/10.1016/j.pharmthera.2005.05.002 ER - TY - JOUR AU - Kappos, L. TI - Oral fingolimod (FTY720) for relapsing multiple sclerosis JA - N. Engl. J. Med. PY - 2006/// VL - 355 SP - 1124 EP - 1140 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1056/NEJMoa052643 N1 - 10.1056/NEJMoa052643 UR - http://dx.doi.org/10.1056/NEJMoa052643 ER - TY - JOUR AU - Budde, K. TI - First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients JA - J. Am. Soc. Nephrol. PY - 2002/// VL - 13 SP - 1073 EP - 1083 PB - Macmillan Publishers Limited. All rights reserved ER - TY - JOUR AU - Pinschewer, D. D. TI - FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory JA - J. Immunol. PY - 2000/// VL - 164 SP - 5761 EP - 5770 PB - Macmillan Publishers Limited. All rights reserved ER - TY - JOUR AU - Moskophidis, D. AU - Lechner, F. AU - Pircher, H. AU - Zinkernagel, R. M. TI - Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells JA - Nature PY - 1993/// VL - 362 SP - 758 EP - 761 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1038/362758a0 N1 - 10.1038/362758a0 UR - http://dx.doi.org/10.1038/362758a0 ER - TY - JOUR AU - Zajac, A. J. TI - Viral immune evasion due to persistence of activated T cells without effector function JA - J. Exp. Med. PY - 1998/// VL - 188 SP - 2205 EP - 2213 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1084/JEM.188.12.2205 N1 - 10.1084/JEM.188.12.2205 UR - http://dx.doi.org/10.1084/JEM.188.12.2205 ER - TY - JOUR AU - Barber, D. L. TI - Restoring function in exhausted CD8 T cells during chronic viral infection JA - Nature PY - 2006/// VL - 439 SP - 682 EP - 687 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1038/nature04444 N1 - 10.1038/nature04444 UR - http://dx.doi.org/10.1038/nature04444 ER - TY - JOUR AU - Brooks, D. G. TI - Interleukin-10 determines viral clearance or persistence in vivo JA - Nature Med. PY - 2006/// VL - 12 SP - 1301 EP - 1309 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1038/nm1492 N1 - 10.1038/nm1492 UR - http://dx.doi.org/10.1038/nm1492 ER - TY - JOUR AU - Matter, M. AU - Odermatt, B. AU - Yagita, H. AU - Nuoffer, J. M. AU - Ochsenbein, A. F. TI - Elimination of chronic viral infection by blocking CD27 signaling JA - J. Exp. Med. PY - 2006/// VL - 203 SP - 2145 EP - 2155 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1084/jem.20060651 N1 - 10.1084/jem.20060651 UR - http://dx.doi.org/10.1084/jem.20060651 ER - TY - JOUR AU - Brooks, D. G. AU - Lee, A. M. AU - Elsaesser, H. AU - McGavern, D. B. AU - Oldstone, M. B. TI - IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection JA - J. Exp. Med. PY - 2008/// VL - 205 SP - 533 EP - 541 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1084/jem.20071948 N1 - 10.1084/jem.20071948 UR - http://dx.doi.org/10.1084/jem.20071948 ER - TY - JOUR AU - Ha, S. J. TI - Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection JA - J. Exp. Med. PY - 2008/// VL - 205 SP - 543 EP - 555 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1084/jem.20071949 N1 - 10.1084/jem.20071949 UR - http://dx.doi.org/10.1084/jem.20071949 ER - TY - JOUR AU - Muller, S. TI - Role of an intact splenic microarchitecture in early lymphocytic choriomeningitis virus production JA - J. Virol. PY - 2002/// VL - 76 SP - 2375 EP - 2383 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1128/jvi.76.5.2375-2383.2002 N1 - 10.1128/jvi.76.5.2375-2383.2002 UR - http://dx.doi.org/10.1128/jvi.76.5.2375-2383.2002 ER - TY - JOUR AU - Altman, J. D. TI - Phenotypic analysis of antigen-specific T lymphocytes JA - Science PY - 1996/// VL - 274 SP - 94 EP - 96 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1126/science.274.5284.94 N1 - 10.1126/science.274.5284.94 UR - http://dx.doi.org/10.1126/science.274.5284.94 ER - TY - JOUR AU - Cembrzynska-Nowak, M. TI - Different antiviral activity and cell specificity of interferon preparations produced by mouse peritoneal cells at 37 degrees C and at 26 degrees C JA - Arch. Immunol. Ther. Exp. (Warsz.) PY - 1989/// VL - 37 SP - 499 EP - 502 PB - Macmillan Publishers Limited. All rights reserved ER - TY - JOUR AU - Merrill, A. H. AU - Sullards, M. C. AU - Allegood, J. C. AU - Kelly, S. AU - Wang, E. TI - Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry JA - Methods PY - 2005/// VL - 36 SP - 207 EP - 224 PB - Macmillan Publishers Limited. All rights reserved M3 - 10.1016/j.ymeth.2005.01.009 N1 - 10.1016/j.ymeth.2005.01.009 UR - http://dx.doi.org/10.1016/j.ymeth.2005.01.009 ER -