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Nature 454, 890-893 (9 July 2008) | doi:10.1038/nature07151;
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Drosophila RNAi screen identifies host genes important for influenza virus replication
All viruses rely on host cell proteins and their associated mechanisms to complete the viral life cycle. Identifying the host molecules that participate in each step of virus replication could provide valuable new targets for antiviral therapy, but this goal may take several decades to achieve with conventional forward genetic screening methods and mammalian cell cultures.
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