Table of contents

indicates content that is available online only

Making the paper: Carl Petersen px

Neighbouring neuron recordings reflect behavioural changes.

doi:10.1038/7206xa


Abstractions px

doi:10.1038/7206xb


From the blogosphere px

doi:10.1038/7206xc


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Editorial

A task of terawatts p805

The world has an abundance of renewable energy to offer, the question is how to harness it.

doi:10.1038/454805a


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Research Highlights

Geophysics: Iceberg smash-up p806

doi:10.1038/454806a


Comparative biology: Animal models p806

doi:10.1038/454806b


Planetary science: Soft metals p806

doi:10.1038/454806c


Climatology: Winter sun p806

doi:10.1038/454806d


Astrophysics: Slow-motion supernovae p806

doi:10.1038/454806e


Zoology: Predatory Lotharios p806

doi:10.1038/454806f


Human history: Digging up data p807

doi:10.1038/454807a


Immunology: Successful delivery p807

doi:10.1038/454807b


Genetics: Appendages of note p807

doi:10.1038/454807c


Materials science: Light beat p807

doi:10.1038/454807d


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Journal Club

Journal club p807

Francis Albarede

doi:10.1038/454807e


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News

Top climate-impacts programme shut p808

National Center for Atmospheric Research axes developing-world initiative.

Jeff Tollefson

doi:10.1038/454808a


Physicists await dark-matter confirmation p808

PAMELA mission offers tantalizing hint of success.

Geoff Brumfiel

doi:10.1038/454808b


Biodiversity body 'lacks science' p809

Swedish researchers criticize credentials of convention.

Daniel Cressey

doi:10.1038/454809a


Four wheels good? p810

With the world's love of cars showing little sign of abating, manufacturers are under increasing pressure to make vehicles less polluting and oil dependent. Duncan Graham-Rowe explores some of the technologies that could keep us on the road.

Duncan Graham-Rowe

doi:10.1038/454810a


The AIDS fight: looking ahead to 2010 p812

As this month's International AIDS Conference in Mexico City ends, Erika Check Hayden asks leaders of the HIV community what they expect to see on the agenda when the conference reconvenes in Vienna in 2010 — the year by which the world has agreed to provide universal access to HIV treatment.

Erika Check Hayden

doi:10.1038/454812a


Anthrax case ignites new forensics field p813

Biochemical method of tracking microbes hits the limelight.

Amber Dance

doi:10.1038/454813a


Large Hadron Collider passes first proton test p815

doi:10.1038/454815a


Environment agency denies plea to cut biofuel goals p815

doi:10.1038/454815b


San Francisco's biotech hub gets lift from Pfizer deal p815

doi:10.1038/454815c


Gorilla numbers doubled in the Congo p815

doi:10.1038/454815d


FDA further tightens conflict of interest policies p815

doi:10.1038/454815e


Hotspot for midges proves to be fertile ground p815

doi:10.1038/454815f


SciFoo blogged p815

doi:10.1038/454815g


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News Feature

Electricity without carbon p816

Nature's News team looks at how much carbon-free energy might ultimately be available — and which sources make most sense.

doi:10.1038/454816a


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Correspondence

Mental health: maybe human troubles don't fit into set categories p824

Paul Reeve & Louigi Addario-Berry

doi:10.1038/454824a


Mental health: don't overlook environment and its risk factors p824

John J. McGrath & Jean-Paul Selten

doi:10.1038/454824b


Mental health: drop ideological baggage in favour of best tools p824

P. Alexander Arguello

doi:10.1038/454824c


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Books and Arts

On the scent p825

For Marcel Proust, the madeleine evoked childhood memories — a new treatment of the science of smell attempts to take our everyday experience of odour to a more insightful level, explains Gary Beauchamp.

doi:10.1038/454825a


Playing to win p826

doi:10.1038/454826a


Challenging stereotypes p827

doi:10.1038/454827a


Bucky's utopian universe p828

doi:10.1038/454828a


In Retrospect: Gödel's proof p829

In today's computer age, the implications of the discovery in formal logic that Newman and Nagel articulated in 1958 are of even broader interest, says Andrew Hodges.

doi:10.1038/454829a


Correction p829

doi:10.1038/454829b


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News and Views

量子力学: 「瞬時に」の速度

Quantum mechanics: The speed of instantly p831

Pairs of quantum-mechanically entangled particles seem to know at once what is happening to each other. Experiments show that even if this signalling is not instantaneous, it must be really, really fast.

Terence G. Rudolph

doi:10.1038/454831a


生化学: 酵素にぴったり合う形

Biochemistry: Fit for an enzyme p832

Certain enzymes that synthesize antibiotics play a game of pass the parcel, handing biosynthetic intermediates from one active site to another. A study reveals the dynamic nature of interactions between the enzyme domains.

Shiven Kapur & Chaitan Khosla

doi:10.1038/454832a


地球科学: 地球内核が固体であることの手堅い証拠

Earth Science: Solid evidence in the inner core p833

The indications are that a solid ball of iron lies at Earth's centre. But only the identification of an elusive seismic signature can confirm the long-standing assumption that it is indeed solid.

Kenneth C. Creager

doi:10.1038/454833a


古生物学: 最後の巨大なカンガルー

Palaeontology: The last giant kangaroo p835

Humans who colonized Australia did not reach Tasmania until thousands of years later — granting the island's giant kangaroos a brief respite before they joined their Australian brethren in oblivion.

Jared Diamond

doi:10.1038/454835a


ナノテクノロジー: 無を形作る

Nanotechnology: Shaping the void p836

A vacuum may be devoid of matter, but its shape is still important. The strength of the Casimir force caused by quantum fluctuations in the space between surfaces is critically dependent on their nanometre-scale shape.

Astrid Lambrecht

doi:10.1038/454836a


免疫学: 予想外の副作用

Immunology: Surprising side effects p837

A drug that normally suppresses an immune response by trapping lymphocytes in lymphoid organs results in the elimination of a chronic viral infection when applied at low doses. Why should this be?

Michael J. Bevan & Pamela J. Fink

doi:10.1038/454837a


自閉症: 家族の絆

Autism: Family connections p838

Autism is a common neurodevelopmental syndrome with a strong genetic component. The study of autistic individuals whose parents are cousins highlights the genetic diversity of this condition.

Daniel H. Geschwind

doi:10.1038/454838a


神経科学: 公認の同期性

Neuroscience: State-sanctioned synchrony p839

A sleepy brain pays little attention to its surroundings, and its neurons are lulled by a common oscillation. As the brain swiftly rouses from this sluggish state, its neurons function more independently.

Scott J. Cruikshank & Barry W. Connors

doi:10.1038/454839a


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Review

セルロース系バイオ燃料のゲノミクス

Genomics of cellulosic biofuels p841

Edward M. Rubin

doi:10.1038/nature07190


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Articles

UCP2はフリーラジカルを低減させることでNPY/AgRPニューロンに対するグレリンの作用を仲介する

UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals p846

Zane B. Andrews, Zhong-Wu Liu, Nicholas Walllingford, Derek M. Erion, Erzsebet Borok, Jeffery M. Friedman, Matthias H. Tschöp, Marya Shanabrough, Gary Cline, Gerald I. Shulman, Anna Coppola, Xiao-Bing Gao, Tamas L. Horvath & Sabrina Diano

doi:10.1038/nature07181


70Sリボソームにおける翻訳終結の構造的基盤

Structural basis for translation termination on the 70S ribosome p852

Martin Laurberg, Haruichi Asahara, Andrei Korostelev, Jianyu Zhu, Sergei Trakhanov & Harry F. Noller

doi:10.1038/nature07115


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Letters

隕石と近地球小惑星の間の組成の違い

Compositional differences between meteorites and near-Earth asteroids p858

P. Vernazza, R. P. Binzel, C. A. Thomas, F. E. DeMeo, S. J. Bus, A. S. Rivkin & A. T. Tokunaga

doi:10.1038/nature07154


「不可解な遠隔作用」の速度の検証

Testing the speed of 'spooky action at a distance' p861

Daniel Salart, Augustin Baas, Cyril Branciard, Nicolas Gisin & Hugo Zbinden

doi:10.1038/nature07121


表面触媒脱水素環化による芳香族前駆体からのフラーレン合成

Fullerenes from aromatic precursors by surface-catalysed cyclodehydrogenation p865

Gonzalo Otero, Giulio Biddau, Carlos Sánchez-Sánchez, Renaud Caillard, María F. López, Celia Rogero, F. Javier Palomares, Noemí Cabello, Miguel A. Basanta, José Ortega, Javier Méndez, Antonio M. Echavarren, Rubén Pérez, Berta Gómez-Lor & José A. Martín-Gago

doi:10.1038/nature07193


北アメリカ氷床の力学と氷期の10万年サイクルの開始

North American ice-sheet dynamics and the onset of 100,000-year glacial cycles p869

R. Bintanja & R. S. W. van de Wal

doi:10.1038/nature07158


PKJKP波の観測から得られた内核のS波異方性と組織

Inner-core shear-wave anisotropy and texture from an observation of PKJKP waves p873

James Wookey & George Helffrich

doi:10.1038/nature07131


不顕性感染とコレラの動態

Inapparent infections and cholera dynamics p877

Aaron A. King, Edward L. Ionides, Mercedes Pascual & Menno J. Bouma

doi:10.1038/nature07084


脳内部状態は行動中のマウスのバレル皮質の膜電位同期性を調節する

Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice p881

James F. A. Poulet & Carl C. H. Petersen

doi:10.1038/nature07150


細胞の自発的な極性出現について

On the spontaneous emergence of cell polarity p886

Steven J. Altschuler, Sigurd B. Angenent, Yanqin Wang & Lani F. Wu

doi:10.1038/nature07119


ショウジョウバエにおけるRNA干渉スクリーニングによってインフルエンザウイルスの複製に重要な宿主遺伝子を同定する

Drosophila RNAi screen identifies host genes important for influenza virus replication p890

Linhui Hao, Akira Sakurai, Tokiko Watanabe, Ericka Sorensen, Chairul A. Nidom, Michael A. Newton, Paul Ahlquist & Yoshihiro Kawaoka

doi:10.1038/nature07151


FTY720の一過的投与は免疫を介した慢性ウイルス感染の排除を促進する

Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection p894

Mary Premenko-Lanier, Nelson B. Moseley, Sarah T. Pruett, Pablo A. Romagnoli & John D. Altman

doi:10.1038/nature07199


哺乳類のメッセンジャーRNAに埋め込まれた不連続なハンマーヘッド型リボザイム

A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA p899

Monika Martick, Lucas H. Horan, Harry F. Noller & William G. Scott

doi:10.1038/nature07117


非リボソームペプチドシンテターゼの動的なチオール化-チオエステラーゼ構造

Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase p903

Dominique P. Frueh, Haribabu Arthanari, Alexander Koglin, David A. Vosburg, Andrew E. Bennett, Christopher T. Walsh & Gerhard Wagner

doi:10.1038/nature07162


サーファクチンシンテターゼの外部チオエステラーゼ選択性に関する構造的基盤

Structural basis for the selectivity of the external thioesterase of the surfactin synthetase p907

Alexander Koglin, Frank Löhr, Frank Bernhard, Vladimir V. Rogov, Dominique P. Frueh, Eric R. Strieter, Mohammad R. Mofid, Peter Güntert, Gerhard Wagner, Christopher T. Walsh, Mohamed A. Marahiel & Volker Dötsch

doi:10.1038/nature07161


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Naturejobs

Prospect

Prospects p913

Expanding your curiosity can lead to more job opportunities.

Paul Smaglik

doi:10.1038/nj7206-913a


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Futures

Subject to change p916

Getting to grips with scientific variables.

Joseph Lachance

doi:10.1038/454916a


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