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Nature 454, 838-839 (14 August 2008) | doi:10.1038/454838a; Published online 13 August 2008
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Assoc. Scientific Manager / Scientific Manager - Biopharmaceutics
- Syngene International
- Bangalore, Karnataka 560099 India
Faculty Positions in Systems Neuroscience
- NYU School of Medicine
- Smilow Research Center
Autism: Family connections
Daniel H. Geschwind1
Abstract
Autism is a common neurodevelopmental syndrome with a strong genetic component. The study of autistic individuals whose parents are cousins highlights the genetic diversity of this condition.
Genetically complex human disorders, such as obesity and Alzheimer's disease, also occur in rare inherited forms — that is, a disease-causing mutation arises that can be passed on to the next generation. Studying such rare mutations is a powerful strategy for gaining insight into the mechanisms of the more common forms of a disease1.
- Daniel H. Geschwind is in the Program in Neurogenetics, Department of Neurology, and at the Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, 710 Westwood Plaza, Los Angeles, California 90095–1769, USA.
Email: dhg@mednet.ucla.edu
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RESEARCH
A genome-wide linkage and association scan reveals novel loci for autismNature Letters to Editor (08 Oct 2009)
