FIGURE 2. Effect of selected siRNAs and inhibitors on Renilla luciferase expression in FVG-R-infected human cells.
From the following article:
Drosophila RNAi screen identifies host genes important for influenza virus replication
Linhui Hao, Akira Sakurai, Tokiko Watanabe, Ericka Sorensen, Chairul A. Nidom, Michael A. Newton, Paul Ahlquist & Yoshihiro Kawaoka
Nature 454, 890-893(14 August 2008)
doi:10.1038/nature07151
a–c, Renilla luciferase activity was measured in FVG-R-infected HEK 293 cells treated with siRNAs against ATP6V0D1 and COX6A1 (a), NXF1 (b) or the indicated mitochondrial electron transport chain inhibitors (c). Inhibitors of complexes III, IV and V inhibited FVG-R-directed Renilla luciferase expression significantly, whereas complex I and II inhibitors had little or no effect. In contrast, the inhibitors had no significant effects on cell viability and Gaussia luciferase expression of a murine leukaemia virus derivative (MLV-GL) that, like FVG-R, depended on VSV G-mediated entry. All experiments were conducted three times in duplicate, with the results reported as mean 
s.d. 3-NPA, 3-nitroproprionic acid.
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