FIGURE 1. Overview of genome-wide RNAi screen to identify host factors involved in influenza virus replication in Drosophila cells.
From the following article:
Drosophila RNAi screen identifies host genes important for influenza virus replication
Linhui Hao, Akira Sakurai, Tokiko Watanabe, Ericka Sorensen, Chairul A. Nidom, Michael A. Newton, Paul Ahlquist & Yoshihiro Kawaoka
Nature 454, 890-893(14 August 2008)
doi:10.1038/nature07151
a, b, Schematic diagrams showing recombinant influenza viruses. Shown are FVG-G, in which genes encoding the HA and NA proteins were replaced with the VSV-G and eGFP genes, respectively (a), and FVG-R, in which the genes encoding the HA and NA were replaced with the VSV-G and Renilla luciferase genes, respectively (b). c, Schematic diagram of the systematic analysis of host genes affecting influenza virus replication and gene expression in Drosophila cells. Experimental details are given in Methods.
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