Access
To read this story in full you will need to login or make a payment (see right).
Technology Feature
Nature 454, 795-798 (7 August 2008) | doi:10.1038/454795a; Published online 6 August 2008
Open Innovation Challenges
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
nature jobs
Clinical Trial Analyst
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Sr. Scientific Manager / Chief Scientific Manager - Discovery Bioanalytical Research and Biotransformation
- Syngene International
- Bangalore, Karnataka 560099 India
Epigenomics: Detailed analysis
Laura Bonetta1
Abstract
Researchers now have access to a burgeoning collection of tools for unravelling the epigenome, which could lead to new drug targets and ways to track disease. Laura Bonetta reports.
Just as DNA mutations can cause disease, so too can changes in gene activity that don't depend on DNA sequence. For example, the addition of methyl groups to cytosines within the promoter regions of a gene, a process known as DNA methylation, typically represses the gene's activity.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Toward a human epigenomeNature Genetics News and Views (01 Dec 2006)
Locking in on the human methylomeNature Biotechnology News and Views (01 Apr 2009)

