Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Article
Nature 454, 646-650 (29 June 2008) | doi:10.1038/nature07061;
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
nature jobs
Professor
- University of Cincinnati and Cincinnati Children's Research Foundation
- Cincinnati, OH
Academic Neuropathologist
- University Hospitals Case Medical Center
- Cleveland, Ohio, USA
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
Reprogramming of somatic cells is a valuable tool to understand the mechanisms of regaining pluripotency and further opens up the possibility of generating patient-specific pluripotent stem cells. Reprogramming of mouse and human somatic cells into pluripotent stem cells, designated as induced pluripotent stem (iPS) cells, has been possible with the expression of the transcription factor quartet Oct4 (also known as Pou5f1), Sox2, c-Myc and Klf4 (refs 1–11).
&
Abstract
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).

